Is neutrophil lymphocyte ratio magic or not?

Aim: To evaluate the predictive value of preoperative ratio neutrophils to lymphocytes (NLR) in distinguishing between benign and malignant masses, as inflammation plays a significant role development emergence cancer.
 Material Method: This retrospective study included 155 patients who underwent surgery due an adnexal mass December 2020 2021 (55 were malignant, 100 benign). Age, parity, tumor stage, chemotherapy, CA 125, CRP, neutrophils, lymphocytes, NLR, recorded. The Mann-Whitney, Chi-square test multiple linear regression used. cut-off values variables determined by calculating areas under receiver operating characteristic curve (ROC) for purposes differential diagnosis presence malignancy, analyzing sensitivity, specificity, positive value, negative likelihood-ratio (LR) (+) values. A P-value 2.79 NLR; sensitivity was found be 59.36%, specificity 75.51%, (PPV) 58.44, 75.58, LR 2.3. At cut-off> 36.9 CA-125; 80.00%, 78.63%, 67.72%, 87.53%, 3.73.
 Conclusion: primary outcome our is that likelihood malignancy patient with NLR of>2.79 2.3 times higher than 3.73 CA-125